Chicken pox virus remains dormant


















Herpes zoster shingles occurs when the virus becomes active again. Chickenpox first occurs as a blister-like skin rash and fever. It takes from days after exposure for someone to develop chickenpox. The sores commonly occur in batches with different stages bumps, blisters, and sores present at the same time. The blisters usually scab over in 5 days.

A person with chickenpox is contagious days before the rash appears and until all blisters have formed scabs. Children with weakened immune systems may have blisters occurring for a prolonged time period. Adults can develop severe pneumonia and other serious complications. Shingles occurs when the virus, which has been inactive for some time, becomes active again.

Severe pain and numbness along nerve pathways, commonly on the trunk or on the face, are present. Explore further. Use this form if you have come across a typo, inaccuracy or would like to send an edit request for the content on this page.

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A research team led by UCL and Erasmus University has found a missing piece to the puzzle of why the virus that causes chickenpox and shingles can remain dormant for decades in human cells. Described in a recent paper in Nature Communications , researchers discovered there is an RNA transcript in the varicella zoster virus VZV , that continues to remain active after a person has recovered from chickenpox.

Previous studies were unable to identify how VZV latency works, partly because, unlike the herpes simplex viruses, which are also alphaherpesviruses that remains dormant after initial infection, there are no animal models of VZV latency. Kinchington, Ronald S. ScienceDaily, 4 June Bar-Ilan University. How dormant infections caused by childhood chicken pox can -- decades later -- trigger shingles. Retrieved January 12, from www. Featured Content.

These induced stem cells are similar to those that occur Most people are infected by several herpes viruses by the time they reach ScienceDaily shares links with sites in the TrendMD network and earns revenue from third-party advertisers, where indicated.



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